Ali Azmoudeh /

Medical imaging · Domain shift

GLIMS-MedNeXt

Brain tumor segmentation under domain shift

Adapting volumetric segmentation models from high-quality MRI to the imaging conditions represented in BraTS Sub-Saharan Africa.

My contribution

First author · Model development and experimental evaluation

I developed and evaluated an ensemble of GLIMS and MedNeXt, using transfer learning, SSA fine-tuning, and fusion experiments to study segmentation performance under domain shift.

Conceptual brain and MRI layers
Conceptual illustration · not experimental output

01 / Problem

What needed solving

MRI quality and data availability vary across imaging settings. A model trained on high-quality scans needs evaluation and adaptation before its results can be trusted on a different domain.

02 / Approach

Methods & data

  • GLIMS + MedNeXt
  • Transfer learning
  • Ensemble fusion
  • PyTorch
  • MONAI
  • 3D MRI segmentation

BraTS GLI for pretraining → BraTS SSA for adaptation and evaluation; four MRI modalities.

  1. Prepare multimodal MRI inputs
  2. Pretrain and adapt the two segmentation models
  3. Fuse predictions and evaluate segmentation quality

03 / Outcome

BraTS-Lighthouse 2025 submission

The ensemble work was published in the MICCAI 2025 challenge proceedings in 2026. The paper reports improved accuracy and robustness on BraTS-SSA. See the publication for its full evaluation protocol.

Research evaluation on BraTS data; clinical deployment has not been established. Conformal risk-control experiments are a separate, ongoing research direction.

Read the published evaluation

Publication

GLIMS-MedNeXt: An Ensemble Framework for Brain MRI Segmentation in Sub-Saharan Africa

Ali Azmoudeh, İlkay Öksüz, Hazım Kemal Ekenel

Segmentation, Classification, and Synthesis for Brain Tumors and Traumatic Brain Injuries · 2026